31st July 2021 @ 2:30 pm (H) Danesmen vs Colne & Nelson Scarborough RUFC Silver Royd, Scalby Road, Scarborough, North Yorkshire
25th September 2021 @ 3:00 pm (A) Danesmen vs Bridlington Bridlington RUFC Dukes Park, Queensgate, Bridlington, East Yorkshire
2nd October 2021 @ 3:00 pm (H) Danesmen vs Pocklington Scarborough RUFC Silver Royd, Scalby Road, Scarborough, North Yorkshire
20th November 2021 @ 2:15 pm (H) Danesmen vs Hull University Scarborough RUFC Silver Royd, Scalby Road, Scarborough, North Yorkshire
4th December 2021 @ 2:15 pm (H) Danesmen vs Goole Scarborough RUFC Silver Royd, Scalby Road, Scarborough, North Yorkshire
January 15 @ 2:15 pm (H) Danesmen vs Bridlington Scarborough RUFC Silver Royd, Scalby Road, Scarborough, North Yorkshire
January 22 @ 2:15 pm (A) Danesmen vs Pocklington Pocklington RUFC Feathers Field, Percy Road, Pocklington, East Yorkshire
February 12 @ 2:15 pm (H) Danesmen vs Malton & Norton Scarborough RUFC Silver Royd, Scalby Road, Scarborough, North Yorkshire
February 19 @ 2:15 pm (H) Danesmen vs Ionians Scarborough RUFC Silver Royd, Scalby Road, Scarborough, North Yorkshire
February 26 @ 2:15 pm (A) Danesmen vs Driffield Driffield RUFC Kellythorpe, Driffield, East Yorkshire
March 12 @ 3:00 pm (A) Danesmen vs Hull University Hull University RUFC Brantingham Park, Brantingham Road, Brough, East Yorkshire
March 26 @ 3:00 pm (H) Danesmen vs Driffield Scarborough RUFC Silver Royd, Scalby Road, Scarborough, North Yorkshire
April 2 @ 3:00 pm (A) Danesmen vs Goole Goole RUFC Westfield Banks, Westfield Lane, Goole, East Yorkshire
April 9 @ 3:00 pm (A) Danesmen vs Barton Barton RUFC Mill Lane, Barrow Upon Humber, Barton, North Lincolnshire
April 9 @ 3:00 pm (H) Danesmen vs Bridlington Scarborough RUFC Silver Royd, Scalby Road, Scarborough, North Yorkshire
